Detalhe da pesquisa
1.
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.
Cell
; 183(3): 636-649.e18, 2020 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33031745
2.
Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory.
Nat Immunol
; 21(12): 1597-1610, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33046889
3.
Pyrin variant E148Q potentiates inflammasome activation and the effect of pathogenic mutations in cis.
Rheumatology (Oxford)
; 63(3): 882-890, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37481715
4.
Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain.
J Biol Chem
; 298(12): 102645, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36309085
5.
NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity.
J Allergy Clin Immunol
; 147(6): 2134-2145.e20, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33378691
6.
Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells.
PLoS Pathog
; 15(2): e1007599, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30811498
7.
Dominant negative OTULIN-related autoinflammatory syndrome.
J Exp Med
; 221(6)2024 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38630025
8.
Stray self-nucleic acids: the emerging drivers of neurodegeneration.
Trends Cell Biol
; 33(6): 451-454, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36907819
9.
Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites.
mBio
; 14(4): e0112923, 2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37449844
10.
Organellar homeostasis and innate immune sensing.
Nat Rev Immunol
; 22(9): 535-549, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197578
11.
Deficiency in coatomer complex I causes aberrant activation of STING signalling.
Nat Commun
; 13(1): 2321, 2022 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484149
12.
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.
Sci Immunol
; 7(75): eabi4611, 2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36112693
13.
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24.
Sci Immunol
; 7(68): eabi6763, 2022 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35148201
14.
Quantification of host-mediated parasite clearance during blood-stage Plasmodium infection and anti-malarial drug treatment in mice.
Int J Parasitol
; 48(12): 903-913, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30176235